Stability Of Protein Pharmaceuticals: Part A: Chemical And Physical Pathways Of Protein Degradation

By Mark C. Manning, Tim J. Ahern, Tim J. Ahern And Mark C. Manning

This first of two volumes examines the chemical and physical mechanisms of degradation processes that occur during drug processing, storage, and delivery. The practical text will be particularly us...

Stability Of Protein Pharmaceuticals: Part B: In Vivo Pathways Of Degradation And Strategies For Protein Stabilization

By Mark C. Manning, Tim J. Ahern, Tim J. Ahern And Mark C. Manning

This first of two volumes examines the chemical and physical mechanisms of degradation processes that occur during drug processing, storage, and delivery. The practical text will be particularly us...

Rational Design Of Stable Protein Formulations: Theory And Practice (Pharmaceutical Biotechnology (13))

By Mark C. Manning, John F. Carpenter

Recombinant proteins and polypeptides continue to be the most important class of biotechnology-derived agents in today's pharmaceutical industry. Over the past few years, our fundamental understand...

Biocatalyst Design For Stability And Specificity

By Keqin Chen, George Georgiou, R Brown, R Berka, Mark C. Manning, Bret A. Shirley, H. Berg, L. Sumner, Robert C. Miller, Lee-Jun C. Wong, C Barnett, Shan S. Wong, David B. Wilson, Ronald Wetzel, Munishwar N. Gupta, Tim Fowler, Jeffrey L. Cleland, Wayne Chen, Chemical Congress Of North America (4th 1991 New York, N.Y.), George H. Lorimer, Rainer Jaenicke, Michael E. Himmel, Frances H. Arnold, Francois Baneyx, Leif Bulow, R. Swanson, J. R. Wild, Dean R. Appling, Daniel I. C. Wang, Julian M. Sturtevant, C. Nick Pace, Ketan Gajiwala, J. B. Bjarnason, B. Asgeirsson, J. W. Fox, John O. Baker, Pablo Umaña, James T. Kellis, Chara Economou, Pascal Martinez, Kyung Pyo Yoon, Mariana Van Dam, Boris A. Chrunyk, Pascal Valax, Anthony A. Gatenby, Gail K. Donaldson, Paul V. Viitanen, Saskia M. Van Der Vies, P. M. Horowitz, Edgar Ong, Jeffrey M. Greenwood, Neil R. Gilkes, R. Anthony J. Warren, Douglas G. Kilburn, M. E. Wales, C. J. Strang, Anice E. Thigpen, Charles K. Barlowe, S. Shoemaker, M. Gritzali, J. H. David Wu, Michael Losiewicz, Timothy J. A. Johnson, A. Sadana, R. R. Raju

Content: Effects of mutations on thermodynamic properties of proteins / Julian M. Sturtevant -- Contribution of hydrogen bonding and the hydrophobic effect to conformational stability of ribonuclea...

Rational Design Of Stable Protein Formulations: Theory And Practice

By Mark C. Manning, John F. Carpenter

Rational Design Of Stable Protein Formulations

By Mark C. Manning, John F. Carpenter, John F. Carpenter; ‎Mark C. Manning

Recombinant proteins and polypeptides continue to be the most important class of biotechnology-derived agents in today's pharmaceutical industry. Over the past few years, our fundamental understand...

Biocatalyst Design For Stability And Specificity : Developed From A Symposium Sponsored By The Division Of Biochemical Technology Of The American Chemical Society At The Fourth Chemical Congress Of North America (202nd National Meeting Of The American Chemical Society), New York, New York, August 25-30, 1991

By Keqin Chen, George Georgiou, R Brown, R Berka, Mark C. Manning, Bret A. Shirley, H. Berg, L. Sumner, Robert C. Miller, Lee-Jun C. Wong, C Barnett, Shan S. Wong, David B. Wilson, Ronald Wetzel, Munishwar N. Gupta, Tim Fowler, Jeffrey L. Cleland, Wayne Chen, George H. Lorimer, Rainer Jaenicke, Michael E. Himmel, Frances H. Arnold, Francois Baneyx, Leif Bulow, R. Swanson, J. R. Wild, Dean R. Appling, Daniel I. C. Wang, Julian M. Sturtevant, C. Nick Pace, Ketan Gajiwala, J. B. Bjarnason, B. Asgeirsson, J. W. Fox, John O. Baker, Pablo Umaña, James T. Kellis, Chara Economou, Pascal Martinez, Kyung Pyo Yoon, Mariana Van Dam, Boris A. Chrunyk, Pascal Valax, Anthony A. Gatenby, Gail K. Donaldson, Paul V. Viitanen, Saskia M. Van Der Vies, P. M. Horowitz, Edgar Ong, Jeffrey M. Greenwood, Neil R. Gilkes, R. Anthony J. Warren, Douglas G. Kilburn, M. E. Wales, C. J. Strang, Anice E. Thigpen, Charles K. Barlowe, S. Shoemaker, M. Gritzali, J. H. David Wu, Michael Losiewicz, Timothy J. A. Johnson, A. Sadana, R. R. Raju

Content: Effects of mutations on thermodynamic properties of proteins / Julian M. Sturtevant -- Contribution of hydrogen bonding and the hydrophobic effect to conformational stability of ribonuclea...

Stability Of Protein Pharmaceuticals

By Mark C. Manning, Kamlesh Patel, Ronald T. Borchardt